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Looking at chemicals in the workplace, it’s not just about knowing what sits in storage. The challenge is keeping track of safety data sheets, inventory thresholds, and all the rules that apply. Trying to manage that with paper files or endless spreadsheets often leads to gaps. That’s why many organizations turn to chemical compliance management software.

In this list, we break down some of the top software solutions designed for chemical compliance. Each one helps centralize records, streamline approvals, and make reporting less of a guessing game. Instead of juggling separate tools, these platforms bring SDS libraries, inventory oversight, and regulatory checks together so compliance becomes part of the daily routine, not a scramble when audits roll around.

1. CampusOptics

At CampusOptics, we focus on providing a full platform for environmental health and safety in higher education. One part of what we do is chemical compliance management software. We built it to help universities and colleges keep track of chemical inventories, manage safety data sheets, and handle waste management without relying on scattered spreadsheets or paper binders. By putting all of this into one system, we make it easier for safety officers and administrators to see what’s on site and make sure regulations are met.

Our platform connects chemical tracking with inspections, incident management, and reporting. This helps reduce mistakes and gives teams the tools to respond faster if issues come up. With mobile access, bar and QR code scanning, and the ability to attach photos or documents, information is available where people actually need it, not just in an office file. We built it with higher education in mind, but the core focus remains the same: making chemical compliance simpler and more manageable.

Key Highlights:

  • Chemical inventory and safety data sheet tracking
  • Hazardous waste management tools
  • Mobile access with bar and QR code scanning
  • Integrated inspections and issue remediation
  • Compliance calendar for scheduled tasks

Services:

  • Chemical compliance management software
  • Hazardous waste and incident tracking
  • Safety inspections and reporting
  • Mobile app for on-site data access
  • Support and training for implementation

Contact Information:

2. Sphera

Sphera provides software designed to support chemical compliance across industries. The company focuses on helping organizations manage safety data sheets, labels, and reporting requirements in a way that reduces manual work and lowers the risk of mistakes. Their chemical compliance management software combines regulatory content with technology so that users can keep up with changes in laws and guidelines. This makes it easier to handle chemical inventory, author documents, and ensure consistency across different operations.

The platform includes tools for material management, product stewardship, and regulatory reporting. By centralizing these processes, Sphera enables teams to work with the same information and maintain compliance without relying on scattered systems. The goal is to simplify complex requirements and give organizations the ability to adapt quickly as regulations evolve.

Key Highlights:

  • Chemical compliance software with regulatory content integration
  • Safety Data Sheet authoring and management
  • Automated labeling and reporting
  • Tools for product stewardship and material management
  • Support for global regulatory frameworks

Services:

  • Chemical compliance management software
  • Regulatory reporting and documentation
  • Hazardous material tracking
  • Centralized product stewardship tools
  • Ongoing support and updates

Contact Information:

  • Website: sphera.com
  • Phone: 888-268-3509
  • LinkedIn: www.linkedin.com/company/sphera
  • Twitter: x.com/SpheraSolutions
  • Facebook: www.facebook.com/SpheraSolutions

3. VelocityEHS

VelocityEHS offers chemical compliance management software as part of its larger environmental health and safety platform. The system allows organizations to cross-check chemical inventories against regulatory lists and keep records aligned with local, state, federal, and international requirements. By managing data at the ingredient level, the software helps identify risks early and supports decisions about safer alternatives.

The platform also provides access to a large library of safety data sheets and allows teams to track chemicals across multiple sites. With mobile access, QR code scanning, and reporting features, the software supports compliance activities both in the office and in the field. This setup helps organizations streamline hazardous chemical reporting, reduce administrative tasks, and stay on top of evolving regulations.

Key Highlights:

  • Chemical compliance and regulatory reporting software
  • Cross-checking chemicals against international lists
  • Ingredient-level tracking and risk identification
  • Access to extensive SDS library with mobile support
  • Integrated inventory tracking across facilities

Services:

  • Chemical compliance management software
  • Regulatory reporting and cross-referencing
  • Hazard communication (HazCom) tools
  • Mobile chemical inventory and SDS access
  • Centralized reporting and dashboards

Contact Information:

  • Website: www.ehs.com
  • Address: 222 Merchandise Mart Plaza, Suite 1750, Chicago, IL 60654
  • Phone: 1.866.919.7922
  • LinkedIn: www.linkedin.com/company/velocityehs
  • Twitter: x.com/velocityehs
  • Facebook: www.facebook.com/velocityehs

4. ComplianceQuest

ComplianceQuest delivers chemical compliance management software that helps organizations automate tasks like safety data sheet handling, chemical inventory tracking, and regulatory reporting. The platform is cloud-based, which means compliance teams across different locations can work with the same data in real time. This setup supports global chemical safety standards, including OSHA HazCom, REACH, and GHS, making it easier for businesses to operate across multiple regions.

The software also integrates workflows for approvals, risk assessments, and audits. By moving away from paper records and disconnected systems, organizations can create a clearer process for chemical compliance. Additional features like mobile access, IoT integration, and dashboards provide visibility into chemical use, storage conditions, and reporting requirements. The focus is on simplifying compliance and giving teams the tools they need to manage chemicals safely and effectively.

Key Highlights:

  • Cloud-based chemical compliance management software
  • Automated workflows for SDS management and reporting
  • Centralized data for multi-site operations
  • Support for global regulatory frameworks like REACH and OSHA HazCom
  • Integration with IoT, mobile tools, and analytics

Services:

  • Chemical compliance management software
  • Safety Data Sheet and labeling management
  • Regulatory reporting and global compliance support
  • Chemical approval workflows and risk assessment
  • Mobile and IoT-enabled monitoring tools

Contact Information:

  • Website: www.compliancequest.com
  • Phone: (408)-458-8343
  • E-mail: info@compliancequest.com
  • LinkedIn: www.linkedin.com/company/compliancequest
  • Twitter: x.com/compliancequest
  • Facebook: www.facebook.com/ComplianceQuest

5. UL Solutions 

UL Solutions provides chemical compliance management software through WERCS Studio. The platform centralizes chemical and material data, supports SDS authoring, and helps keep labeling and documentation aligned with current rules. The software connects product stewardship tasks with regulatory content so teams can review substances, apply policies, and create the right documents for different regions.

WERCS Studio focuses on practical workflows. Users manage inventories, check materials against regulations, and distribute up-to-date SDS and labels. The system is built to integrate with existing tools and share information across the supply chain. The aim is simple control of chemical data from product design through disposal.

Key Highlights:

  • Chemical compliance management software with integrated regulatory content
  • SDS authoring and labeling across regions
  • Centralized material and product data
  • Policy management for chemical use
  • Integration options for internal systems

Services:

  • Chemical compliance management software
  • SDS authoring and document distribution
  • Regulatory checks for substances and products
  • Chemical policy setup and enforcement
  • Support for supply chain transparency

Contact Information:

  • Website: www.ul.com
  • Address: 2601 SE Otis Corley Drive, Bentonville, Arkansas, 72712
  • Phone: +1.479.286.2300
  • LinkedIn: www.linkedin.com/company/ulsolutions
  • Twitter: x.com/UL_Solutions
  • Facebook: www.facebook.com/ULSolutionsGlobal
  • Instagram: www.instagram.com/ul_solutions

6. Scitegrity

Scitegrity offers chemical compliance management focused on dangerous goods assessment. DG Assessor helps identify explosive, self reactive, and energetic chemicals so shipments follow international rules. The goal is to make classification clearer and reduce the chance of non-compliant transport.

The approach is straightforward. Users check chemicals against transport regulations and get guidance that supports safe shipping and documentation. This helps teams decide packaging, labeling, and reporting without chasing scattered sources.

Key Highlights:

  • Chemical compliance management for dangerous goods
  • Support for classification and shipping decisions
  • Focus on explosive and energetic substances
  • Practical guidance for safe transport
  • Streamlined documentation support

Services:

  • Dangerous goods assessment software
  • Chemical classification checks for transport
  • Compliance guidance for labeling and packaging
  • Document support for shipping workflows
  • User support for setup and use

Contact Information:

  • Website: www.scitegrity.com
  • Address: Discovery Park Enterprise Zone, Ramsgate Road, Sandwich, Kent, CT13 9FF, UK
  • E-mail: contact@scitegrity.com
  • LinkedIn: www.linkedin.com/company/scitegrity

7. MasterControl

MasterControl provides quality management software that supports chemical compliance management needs in regulated environments. Teams use the platform to control documents, training, and quality events tied to chemical handling and safety workflows. The system helps organize approvals, keep records audit ready, and standardize how procedures roll out across sites.

The platform connects people and data so compliance tasks are easier to track. Document changes can trigger training, and audits pull from one source of truth. For chemical programs, this means SDS control, procedure alignment, and clear evidence for inspections.

Key Highlights:

  • Quality platform that supports chemical compliance workflows
  • Centralized document and training control
  • Audit readiness with connected records
  • Workflow routing for approvals and changes
  • Cloud deployment for multi-site teams

Services:

  • Chemical compliance management support within QMS
  • Document control and training management
  • Audit and corrective action workflows
  • Procedure and approval routing
  • Implementation guidance and support

Contact Information:

  • Website: www.mastercontrol.com
  • Address: 6350 South 3000 East, Salt Lake City, Utah 84121
  • Phone: +1-866-747-8767
  • E-mail: info@mastercontrol.com
  • LinkedIn: www.linkedin.com/company/mastercontrol
  • Twitter: x.com/MCMasterControl
  • Facebook: www.facebook.com/MasterControlInc

8. 3E

3E provides chemical compliance management through 3E Protect. The service gives access to a large set of SDS and tools to manage those documents across facilities. The aim is quick access to accurate safety information and better control of chemical records.

3E Protect supports day-to-day needs like locating the right SDS, updating locations, and keeping site binders current. This helps teams meet right-to-know requirements and keep chemical information available in the field and in the office.

Key Highlights:

  • Chemical compliance management with SDS access
  • Centralized SDS control across sites
  • Support for right-to-know requirements
  • Tools for quick lookup and updates
  • Help available for emergencies

Services:

  • SDS and chemical management software
  • SDS search, organization, and distribution
  • Site-level binder maintenance
  • Compliance support for labeling and access
  • User assistance and onboarding

Contact Information:

  • Website: www.3eco.com
  • Address: 3207 Grey Hawk Court Carlsbad, CA 92010, USA
  • Phone: +1 760-602-8700
  • E-mail: support@3eco.com
  • LinkedIn: www.linkedin.com/company/3e-safer-world
  • Twitter: x.com/3E_Safer_World
  • Facebook: www.facebook.com/3ESaferWorld
  • Instagram: www.instagram.com/3e_safer_world

9. Transition Technologies

TT-AS offers EMS as a web based system for environmental reporting. The platform helps teams collect, store, and analyze operational data with strong reporting and security. EMS supports configurable forms and Excel based formulas, so organizations can adapt reports without heavy development. The client server setup handles multiple data sources and databases. EMS fits office and field work since users can access it from any location.

For chemical compliance management, EMS can sit at the core of record keeping and reporting. TT-AS enables teams to keep data in one place, apply user access levels, and export reports to PDF or Excel. This makes routine compliance tasks more consistent and easier to verify. The focus is simple setup, robust reporting, and faster project delivery.

Key Highlights:

  • Web based EMS with secure access
  • Robust reporting with export to PDF or Excel
  • Configurable forms using Excel based formulas
  • Multi database support and data history
  • Scalable client server architecture

Services:

  • Chemical compliance management software support within EMS workflows
  • Environmental reporting configuration and customization
  • Data collection, storage, and analysis tools
  • User authentication and role based access
  • Implementation assistance and demos

Contact Information:

  • Website: www.ttas.pl
  • Address: Burakowska 14, 01-066 Warszawa, Poland
  • Phone: +48 22 232 36 36
  • E-mail: info@ttas.pl
  • LinkedIn: www.linkedin.com/company/tt-as

10. QT9 Software

QT9 Software provides tools that support chemical compliance across production and quality. The QMS helps automate audits, document control, CAPAs, and training with alignment to common standards. The ERP and MRP add inventory, batch planning, and formula scheduling in one system. This setup gives chemical manufacturers a clearer view of records and workflows.

For chemical compliance management, QT9 centralizes documents and data used in day to day operations. Teams manage procedures, training, and production details in one place, which helps during inspections and internal checks. The software is built to reduce duplicate work and keep information current across sites.

Key Highlights:

  • QMS for document, audit, CAPA, and training control
  • ERP for production, inventory, and regulatory data
  • MRP for batch and formula planning
  • Single environment to coordinate operations
  • Supports common compliance workflows

Services:

  • Chemical compliance management software across QMS, ERP, and MRP
  • Document and training management
  • Inventory and batch traceability
  • Audit and corrective action workflows
  • Onboarding and user support

Contact Information:

  • Website: qt9software.com
  • Address: Bohereencaol, Killarney, Co. Kerry, V93 W9AK, Ireland
  • Phone: +353 087 689 5785
  • E-mail: info@qt9software.ie
  • LinkedIn: www.linkedin.com/company/qt9-software
  • Twitter: x.com/qt9software
  • Facebook: www.facebook.com/QT9software

11. CIRS Group

CIRS Group provides ChemRadar as a scanning tool for chemical compliance risks. The platform lets users look up substances across global inventories, GHS classifications, UN numbers, and regional rules. ChemRadar highlights changes and notices so teams can react to updates without manual tracking. The focus is quick search, clear status, and coverage across markets.

For chemical compliance management, ChemRadar helps identify obligations early. Users can screen CAS numbers, check lists like REACH or TSCA, and understand restrictions that could affect products and sourcing. This reduces guesswork and supports decisions before procurement or shipment.

Key Highlights:

  • Compliance risk screening across global inventories
  • GHS classification and UN number lookup
  • Updates and notices on regulatory changes
  • Tools for PFAS and food contact checks
  • Support for import, export, and market rules

Services:

  • Chemical compliance management software for screening and research
  • Global chemical inventory and list checks
  • Regulatory alerts and updates
  • Guidance resources and news
  • Multi region contact support

Contact Information:

  • Website: www.chemradar.com
  • Phone: +1 703 520 1420 
  • E-mail: chemicals@cirs-group.com

12. Cority

Cority provides chemical compliance management software as part of its environmental platform. The system helps organizations keep safety data sheets in one place, track on site inventories, and manage approvals before materials are used. By combining SDS access with inventory thresholds and approval workflows, Cority makes it easier to avoid over storage and meet regulatory limits. Mobile access is built in, so teams can scan barcodes, search records, and manage tasks in the field as well as in the office.

The software supports compliance through labeling, hazard communication, and incident readiness. With pre screen tools, materials can be checked against CAS based risks before approval. This helps prevent issues early and keeps documentation consistent across locations. Cority focuses on providing one environment for chemical management from request to disposal, with reporting and oversight included.

Key Highlights:

  • Chemical compliance management software with SDS library
  • Inventory tracking with storage thresholds
  • Pre screen and approval workflows for new materials
  • GHS and WHMIS labeling support
  • Mobile access through barcode scanning and workflows

Services:

  • Chemical compliance management software
  • SDS and labeling management
  • Inventory tracking and approval workflows
  • Hazard communication tools
  • Mobile support for field teams

Contact Information:

  • Website: www.cority.com
  • Address: 121 King St West Suite 810 Toronto, ON M5H 3X7
  • Phone: 1-416-863-6800

13. OECD

OECD develops and maintains the International Uniform Chemical Information Database (IUCLID) together with the European Chemicals Agency. IUCLID is software used to record, store, and share data on chemicals. It is applied by both regulators and industry to meet reporting obligations under global frameworks. The platform captures harmonised data elements, supporting international cooperation and helping reduce duplicate testing of substances.

For chemical compliance management, IUCLID offers a way to structure chemical information consistently across countries. It can be customized for different contexts and integrated with other tools. The system supports regulatory programmes such as REACH and other national rules, making it a core part of how chemical data is exchanged globally.

Key Highlights:

  • Chemical compliance management software for regulatory use
  • Developed and maintained with ECHA
  • Customisable and integrable with other systems
  • Supports OECD harmonised templates and guidelines
  • Used by regulators and industry worldwide

Services:

  • Chemical compliance management software
  • Data recording, storage, and exchange tools
  • Customisation and integration options
  • Support for global regulatory programmes
  • Guidance on harmonised data formats

Contact Information:

  • Website: www.oecd.org
  • E-mail: ehs.contact@oecd.org
  • LinkedIn: www.linkedin.com/company/organisation-eco-cooperation-development
  • Twitter: x.com/OECD
  • Facebook: www.facebook.com/theOECD
  • Instagram: www.instagram.com/the_oecd

Conclusion

Wrapping up, chemical compliance management software isn’t really about ticking boxes or just staying out of trouble with regulators. It’s about having a clear handle on what’s in your facilities, knowing how those substances are being used, and making sure people have the right information when they need it. Paper systems and scattered spreadsheets can only go so far before mistakes creep in, and that’s usually when issues show up.

The software pulls those moving parts together into something more manageable. Safety data sheets, approvals, reporting thresholds, labeling − all the pieces sit in one place. That means less chasing down files and more time focusing on the actual work. Every organization will have its own reasons for putting a system like this in place, but the common thread is simple: it makes compliance less of a constant headache and more of a routine process you can keep up with.